Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain

BACKGROUND: We previously developed a thrombus-induced ischemic pain (TIIP) animal model, which was characterized by chronic bilateral mechanical allodynia without thermal hyperalgesia (TH). On the other hand we had shown that intraplantar injection of acidic saline facilitated ATP-induced pain, whi...

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Detalles Bibliográficos
Autores principales: Kwon, Soon-Gu, Roh, Dae-Hyun, Yoon, Seo-Yeon, Moon, Ji-Young, Choi, Sheu-Ran, Choi, Hoon-Seong, Kang, Suk-Yun, Han, Ho-Jae, Beitz, Alvin J, Oh, Seog Bae, Lee, Jang-Hern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895685/
https://www.ncbi.nlm.nih.gov/pubmed/24401144
http://dx.doi.org/10.1186/1744-8069-10-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895685/
https://www.ncbi.nlm.nih.gov/pubmed/24401144
http://dx.doi.org/10.1186/1744-8069-10-2

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