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Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples
BACKGROUND: DNA methylation plays crucial roles in epigenetic gene regulation in normal development and disease pathogenesis. Efficient and accurate quantification of DNA methylation at single base resolution can greatly advance the knowledge of disease mechanisms and be used to identify potential b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895702/ https://www.ncbi.nlm.nih.gov/pubmed/24406024 http://dx.doi.org/10.1186/1480-9222-16-1 |