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Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples

BACKGROUND: DNA methylation plays crucial roles in epigenetic gene regulation in normal development and disease pathogenesis. Efficient and accurate quantification of DNA methylation at single base resolution can greatly advance the knowledge of disease mechanisms and be used to identify potential b...

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Detalles Bibliográficos
Autores principales:	Lee, Yew Kok, Jin, Shengnan, Duan, Shiwei, Lim, Yen Ching, Ng, Desmond PY, Lin, Xueqin Michelle, Yeo, George SH, Ding, Chunming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895702/ https://www.ncbi.nlm.nih.gov/pubmed/24406024 http://dx.doi.org/10.1186/1480-9222-16-1

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