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Neurodegeneration progresses despite complete elimination of clinical relapses in a mouse model of multiple sclerosis

BACKGOUND: Multiple Sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives the relapse-remitting stage and neurodegeneration represents the principal substrate of secondary progression. In contrast to the increasing number of effecti...

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Detalles Bibliográficos
Autores principales: Hampton, David W, Serio, Andrea, Pryce, Gareth, Al-Izki, Sarah, Franklin, Robin JM, Giovannoni, Gavin, Baker, David, Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895761/
https://www.ncbi.nlm.nih.gov/pubmed/24364862
http://dx.doi.org/10.1186/2051-5960-1-84