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Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice
BACKGROUND: Most tympanic membrane (TM) perforations heal spontaneously, but approximately 10-20% remain open as chronic TM perforations. Chronic perforations can lead to an impaired hearing ability and recurrent middle ear infections. Traditionally, these perforations must be surgically closed, whi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895791/ https://www.ncbi.nlm.nih.gov/pubmed/24393366 http://dx.doi.org/10.1186/1479-5876-12-5 |