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Exosomes are natural carriers of exogenous siRNA to human cells in vitro

BACKGROUND: Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA. As exosomes naturally carry RNA between cells, these particles might be useful in gene cancer therapy to deliver therapeutic short interfe...

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Detalles Bibliográficos
Autores principales: Shtam, Tatyana A, Kovalev, Roman A, Varfolomeeva, Elena Yu, Makarov, Evgeny M, Kil, Yury V, Filatov, Michael V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895799/
https://www.ncbi.nlm.nih.gov/pubmed/24245560
http://dx.doi.org/10.1186/1478-811X-11-88