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Exosomes are natural carriers of exogenous siRNA to human cells in vitro
BACKGROUND: Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA. As exosomes naturally carry RNA between cells, these particles might be useful in gene cancer therapy to deliver therapeutic short interfe...
Autores principales: | Shtam, Tatyana A, Kovalev, Roman A, Varfolomeeva, Elena Yu, Makarov, Evgeny M, Kil, Yury V, Filatov, Michael V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895799/ https://www.ncbi.nlm.nih.gov/pubmed/24245560 http://dx.doi.org/10.1186/1478-811X-11-88 |
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