Membrane TNF-alpha-activated programmed necrosis is mediated by Ceramide-induced reactive oxygen species

BACKGROUND: Programmed necrosis is a form of caspase-independent cell death whose molecular regulation is poorly understood. While tumor necrosis factor-alpha (TNF-α) has been identified as an activator of programmed necrosis, the specific context under which this can happen is unclear. Recently we...

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Detalles Bibliográficos
Autores principales: Ardestani, Shidrokh, Deskins, Desirae L, Young, Pampee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895838/
https://www.ncbi.nlm.nih.gov/pubmed/24180579
http://dx.doi.org/10.1186/1750-2187-8-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895838/
https://www.ncbi.nlm.nih.gov/pubmed/24180579
http://dx.doi.org/10.1186/1750-2187-8-12

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