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Fast selection of miRNA candidates based on large-scale pre-computed MFE sets of randomized sequences

BACKGROUND: Small RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of...

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Detalles Bibliográficos
Autores principales:	Warris, Sven, Boymans, Sander, Muiser, Iwe, Noback, Michiel, Krijnen, Wim, Nap, Jan-Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895842/ https://www.ncbi.nlm.nih.gov/pubmed/24418292 http://dx.doi.org/10.1186/1756-0500-7-34

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