Cargando…

HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells

BACKGROUND: Hypoxia is a major driving force in vascularization and vascular remodeling. Pharmacological inhibition of prolyl hydroxylases (PHDs) leads to an oxygen-independent and long-lasting activation of hypoxia-inducible factors (HIFs). Whereas effects of HIF-stabilization on transcriptional re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weidemann, Alexander, Breyer, Johannes, Rehm, Margot, Eckardt, Kai-Uwe, Daniel, Christoph, Cicha, Iwona, Giehl, Klaudia, Goppelt-Struebe, Margarete
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895861/ https://www.ncbi.nlm.nih.gov/pubmed/24144209 http://dx.doi.org/10.1186/1478-811X-11-80

Ejemplares similares

Actin-Mediated Gene Expression Depends on RhoA and Rac1 Signaling in Proximal Tubular Epithelial Cells
por: Giehl, Klaudia, et al.
Publicado: (2015)

Cell type-specific regulation of CCN2 protein expression by PI3K–AKT–FoxO signaling
por: Samarin, Jana, et al.
Publicado: (2009)

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
por: Villalba, Martin, et al.
Publicado: (2001)

Dynamic reorganization of the actin cytoskeleton
por: Letort, Gaëlle, et al.
Publicado: (2015)

The Non-Catalytic Carboxyl-Terminal Domain of ARFGAP1 Regulates Actin Cytoskeleton Reorganization by Antagonizing the Activation of Rac1
por: Siu, Ka Yu, et al.
Publicado: (2011)

HIF stabilization inhibits renal epithelial cell migration and is associated with cytoskeletal alterations
por: Müller, Simon, et al.
Publicado: (2018)

Jak3 Enables Chemokine-Dependent Actin Cytoskeleton Reorganization by Regulating Cofilin and Rac/Rhoa GTPases Activation
por: Ambriz-Peña, Xochitl, et al.
Publicado: (2014)

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton
por: Yadav, Manoj, et al.
Publicado: (2020)

Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton
por: Lambert, Mireille, et al.
Publicado: (2002)

Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress
por: Schley, Gunnar, et al.
Publicado: (2020)

F-actin cytoskeleton reorganization is associated with hepatic stellate cell activation
por: CUI, XIAODONG, et al.
Publicado: (2014)

Role of Actin Cytoskeleton Reorganization in Polarized Secretory Traffic at the Immunological Synapse
por: Calvo, Victor, et al.
Publicado: (2021)

Roles of Small GTPase Rac1 in the Regulation of Actin Cytoskeleton during Dengue Virus Infection
por: Wang, Jia-Li, et al.
Publicado: (2010)

Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells
por: Zuehlke, Jonathan, et al.
Publicado: (2012)

Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread
por: El Najjar, Farah, et al.
Publicado: (2016)

Actin Up: An Overview of the Rac GEF Dock1/Dock180 and Its Role in Cytoskeleton Rearrangement
por: Koubek, Emily J., et al.
Publicado: (2022)

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway
por: Grampp, Steffen, et al.
Publicado: (2017)

Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization
por: Machesky, Laura M., et al.
Publicado: (1997)

TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase
por: Goncharova, Elena, et al.
Publicado: (2004)

Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis
por: Uetaki, Megumi, et al.
Publicado: (2022)

PI3K p110α Isoform-Dependent Rho GTPase Rac1 Activation Mediates H(2)S-Promoted Endothelial Cell Migration via Actin Cytoskeleton Reorganization
por: Zhang, Li-Jia, et al.
Publicado: (2012)

Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches
por: Byrne, Kate M., et al.
Publicado: (2016)

Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activation
por: Ye, Ya-Ping, et al.
Publicado: (2018)

Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton
por: Stavoe, Andrea K.H., et al.
Publicado: (2012)

A complex microdeletion 17q12 phenotype in a patient with recurrent de novo membranous nephropathy
por: Hinkes, Bernward, et al.
Publicado: (2012)

Reorganization of the nuclear lamina and cytoskeleton in adipogenesis
por: Verstraeten, Valerie L. R. M., et al.
Publicado: (2011)

Distinct Mesenchymal Alterations in N-Cadherin and E-Cadherin Positive Primary Renal Epithelial Cells
por: Keller, Christof, et al.
Publicado: (2012)

Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry
por: Gorudko, Irina V., et al.
Publicado: (2013)

ARHGEF4-mediates the actin cytoskeleton reorganization of hepatic stellate cells in 3-dimensional collagen matrices
por: Zhang, Xiaowei, et al.
Publicado: (2019)

A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex
por: Xu, Xuehua, et al.
Publicado: (2012)

Analysis of matrix-dependent cell migration by a barrier migration assay
por: Kroening, S, et al.
Publicado: (2009)

Vav1 Phosphorylation Is Induced by β2 Integrin Engagement on Natural Killer Cells Upstream of Actin Cytoskeleton and Lipid Raft Reorganization
por: Riteau, Béatrice, et al.
Publicado: (2003)

Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro
por: Lv, Zhimei, et al.
Publicado: (2016)

Taking control: reorganization of the host cytoskeleton by Chlamydia
por: Wesolowski, Jordan, et al.
Publicado: (2017)

Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton
por: He, Yuan, et al.
Publicado: (2013)

Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells
por: Hage, Beatrix, et al.
Publicado: (2009)

Actin cytoskeleton in angiogenesis
por: Yadunandanan Nair, Nidhi, et al.
Publicado: (2022)

Wdr1-Dependent Actin Reorganization in Platelet Activation
por: Dasgupta, Swapan K., et al.
Publicado: (2016)

Small G Rac1 is involved in replication cycle of dengue serotype 2 virus in EAhy926 cells via the regulation of actin cytoskeleton
por: Zhang, Jing, et al.
Publicado: (2016)

ELMO proteins transduce G protein-coupled receptor signal to control reorganization of actin cytoskeleton in chemotaxis of eukaryotic cells
por: Xu, Xuehua, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_99l02ug1tfve24k8ihrr2bg6at