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Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice

Post-operative cognitive dysfunction (POCD) is associated with increased cost of care, morbidity, and mortality. However, its pathogenesis remains largely to be determined. Specifically, it is unknown why elderly patients are more likely to develop POCD and whether POCD is dependent on general anest...

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Detalles Bibliográficos
Autores principales: Xu, Zhipeng, Dong, Yuanlin, Wang, Hui, Culley, Deborah J., Marcantonio, Edward R., Crosby, Gregory, Tanzi, Rudolph E., Zhang, Yiying, Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895908/
https://www.ncbi.nlm.nih.gov/pubmed/24441878
http://dx.doi.org/10.1038/srep03766