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Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice
Post-operative cognitive dysfunction (POCD) is associated with increased cost of care, morbidity, and mortality. However, its pathogenesis remains largely to be determined. Specifically, it is unknown why elderly patients are more likely to develop POCD and whether POCD is dependent on general anest...
Autores principales: | Xu, Zhipeng, Dong, Yuanlin, Wang, Hui, Culley, Deborah J., Marcantonio, Edward R., Crosby, Gregory, Tanzi, Rudolph E., Zhang, Yiying, Xie, Zhongcong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895908/ https://www.ncbi.nlm.nih.gov/pubmed/24441878 http://dx.doi.org/10.1038/srep03766 |
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