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One-pot synthesis of cyanohydrin derivatives from alkyl bromides via incorporation of two one-carbon components by consecutive radical/ionic reactions

The consecutive radical/ionic reaction consisting of radical formylation of alkyl bromides and nucleophilic addition of a cyanide ion was investigated, which gave moderate to good yields of cyanohydrin derivatives in one-pot.

Detalles Bibliográficos
Autores principales: Sumino, Shuhei, Fusano, Akira, Okai, Hiroyuki, Fukuyama, Takahide, Ryu, Ilhyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896227/
https://www.ncbi.nlm.nih.gov/pubmed/24454568
http://dx.doi.org/10.3762/bjoc.10.12