Synthesis and biological activity of N-substituted-tetrahydro-γ-carbolines containing peptide residues

The synthesis of novel peptide conjugates of N-substituted-tetrahydro-γ-carbolines has been performed using the sequence of the Ugi multicomponent reaction and Cu(I)-catalyzed click chemistry. The effect of obtained γ-carboline–peptide conjugates on the rat liver mitochondria was evaluated. It was f...

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Detalles Bibliográficos
Autores principales: Sokolova, Nadezhda V, Nenajdenko, Valentine G, Sokolov, Vladimir B, Vinogradova, Daria V, Shevtsova, Elena F, Dubova, Ludmila G, Bachurin, Sergey O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896248/
https://www.ncbi.nlm.nih.gov/pubmed/24454569
http://dx.doi.org/10.3762/bjoc.10.13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896248/
https://www.ncbi.nlm.nih.gov/pubmed/24454569
http://dx.doi.org/10.3762/bjoc.10.13

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