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NO-independent stimulation or activation of soluble guanylyl cyclase during early reperfusion limits infarct size

AIMS: Guanylyl cyclase-cyclic guanosine monophosphate signalling plays an important role in endogenous cardioprotective signalling. The aim was to assess the potential of direct pharmacological activation and stimulation of soluble guanylyl cyclase, targeting different redox states of the enzyme, to...

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Detalles Bibliográficos
Autores principales: Bice, Justin S., Keim, Yvonne, Stasch, Johannes-Peter, Baxter, Gary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896250/
https://www.ncbi.nlm.nih.gov/pubmed/24259501
http://dx.doi.org/10.1093/cvr/cvt257