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The microRNA-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids

MicroRNA-126 (miR-126) is a microRNA predominately expressed by endothelial cells and controls angiogenesis. We found miR-126 was required for the innate response to pathogen-associated nucleic acids, and that miR-126-deficient mice had increased susceptibility to pseudotyped-HIV infection. miRNA pr...

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Detalles Bibliográficos
Autores principales: Agudo, Judith, Ruzo, Albert, Tung, Navpreet, Salmon, Hélène, Leboeuf, Marylène, Hashimoto, Daigo, Becker, Christian, Garrett-Sinha, Lee-Ann, Baccarini, Alessia, Merad, Miriam, Brown, Brian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896265/
https://www.ncbi.nlm.nih.gov/pubmed/24270517
http://dx.doi.org/10.1038/ni.2767