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Novel N-substituted aminobenzamide scaffold derivatives targeting the dipeptidyl peptidase-IV enzyme

BACKGROUND: The dipeptidyl peptidase-IV (DPP-IV) enzyme is considered a pivotal target for controlling normal blood sugar levels in the body. Incretins secreted in response to ingestion of meals enhance insulin release to the blood, and DPP-IV inactivates these incretins within a short period and st...

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Detalles Bibliográficos
Autores principales: Al-Balas, Qosay A, Sowaileh, Munia F, Hassan, Mohammad A, Qandil, Amjad M, Alzoubi, Karem H, Mhaidat, Nizar M, Almaaytah, Ammar M, Khabour, Omar F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896277/
https://www.ncbi.nlm.nih.gov/pubmed/24470754
http://dx.doi.org/10.2147/DDDT.S53522