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Novel N-substituted aminobenzamide scaffold derivatives targeting the dipeptidyl peptidase-IV enzyme
BACKGROUND: The dipeptidyl peptidase-IV (DPP-IV) enzyme is considered a pivotal target for controlling normal blood sugar levels in the body. Incretins secreted in response to ingestion of meals enhance insulin release to the blood, and DPP-IV inactivates these incretins within a short period and st...
Autores principales: | Al-Balas, Qosay A, Sowaileh, Munia F, Hassan, Mohammad A, Qandil, Amjad M, Alzoubi, Karem H, Mhaidat, Nizar M, Almaaytah, Ammar M, Khabour, Omar F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896277/ https://www.ncbi.nlm.nih.gov/pubmed/24470754 http://dx.doi.org/10.2147/DDDT.S53522 |
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