Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration

The aim of this study was to investigate the feasibility of using spray granulation as a drying method to convert phospholipid (PL)-sodium deoxycholate (SDC)-mixed micelles (MMs) containing a water-insoluble drug to a solid dosage form and to evaluate how drugs with significantly different physicoch...

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Detalles Bibliográficos
Autores principales: Lv, Qingyuan, Li, Xianyi, Shen, Baode, Xu, He, Shen, Chengying, Dai, Ling, Bai, Jinxia, Yuan, Hailong, Han, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896289/
https://www.ncbi.nlm.nih.gov/pubmed/24531119
http://dx.doi.org/10.2147/IJN.S56215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896289/
https://www.ncbi.nlm.nih.gov/pubmed/24531119
http://dx.doi.org/10.2147/IJN.S56215

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