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The regioselective synthesis of spirooxindolo pyrrolidines and pyrrolizidines via three-component reactions of acrylamides and aroylacrylic acids with isatins and α-amino acids

The regioselective three-component condensation of azomethine ylides derived from isatins and α-amino acids with acrylamides or aroylacrylic acids as dipolarophiles has been realized through a one-pot 1,3-dipolar cycloaddition protocol. Decarboxylation of 2'-aroyl-2-oxo-1,1',2,2',5�...

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Detalles Bibliográficos
Autores principales: Pavlovskaya, Tatyana L, Yaremenko, Fedor G, Lipson, Victoria V, Shishkina, Svetlana V, Shishkin, Oleg V, Musatov, Vladimir I, Karpenko, Alexander S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896290/
https://www.ncbi.nlm.nih.gov/pubmed/24454564
http://dx.doi.org/10.3762/bjoc.10.8