Targeting Cadherin-17 Inactivates Ras/Raf/MEK/ERK Signaling and Inhibits Cell Proliferation in Gastric Cancer

Cadherin-17 (CDH17), one member of 7D-cadherin superfamily, was overexpressed in gastric cancer (GC) and was associated with poor survival, tumor recurrence, metastasis, and advanced tumor stage. So far the cellular function and signaling mechanism of CDH17 in GC remains unclear. In this study, we s...

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Detalles Bibliográficos
Autores principales: Lin, Zhaohu, Zhang, Chao, Zhang, Meifang, Xu, Danqing, Fang, Yanfen, Zhou, Zheng, Chen, Xiaolong, Qin, Ning, Zhang, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896370/
https://www.ncbi.nlm.nih.gov/pubmed/24465527
http://dx.doi.org/10.1371/journal.pone.0085296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896370/
https://www.ncbi.nlm.nih.gov/pubmed/24465527
http://dx.doi.org/10.1371/journal.pone.0085296

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