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Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering

Transcription activator-like (TAL) effector nucleases (TALENs) have enabled the introduction of targeted genetic alterations into a broad range of cell lines and organisms. These customizable nucleases are comprised of programmable sequence-specific DNA-binding modules derived from TAL effector prot...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Gaj, Thomas, Patterson, James T., Sirk, Shannon J., Barbas III, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896395/
https://www.ncbi.nlm.nih.gov/pubmed/24465685
http://dx.doi.org/10.1371/journal.pone.0085755