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Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering
Transcription activator-like (TAL) effector nucleases (TALENs) have enabled the introduction of targeted genetic alterations into a broad range of cell lines and organisms. These customizable nucleases are comprised of programmable sequence-specific DNA-binding modules derived from TAL effector prot...
Autores principales: | Liu, Jia, Gaj, Thomas, Patterson, James T., Sirk, Shannon J., Barbas III, Carlos F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896395/ https://www.ncbi.nlm.nih.gov/pubmed/24465685 http://dx.doi.org/10.1371/journal.pone.0085755 |
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