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The Interaction of the Atm Genotype with Inflammation and Oxidative Stress

In ataxia-telangiectasia (A–T) the death of neurons is associated with the loss of neuronal cell cycle control. In most Atm(−/−) mouse models, however, these cell cycle anomalies are present but the phenotype of neuronal cell loss found in humans is not. Mouse Atm (−/−) neurons re-enter a cell cycle...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Hui, Chin Wai, Li, Jiali, Herrup, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896418/
https://www.ncbi.nlm.nih.gov/pubmed/24465754
http://dx.doi.org/10.1371/journal.pone.0085863