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The Interaction of the Atm Genotype with Inflammation and Oxidative Stress
In ataxia-telangiectasia (A–T) the death of neurons is associated with the loss of neuronal cell cycle control. In most Atm(−/−) mouse models, however, these cell cycle anomalies are present but the phenotype of neuronal cell loss found in humans is not. Mouse Atm (−/−) neurons re-enter a cell cycle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896418/ https://www.ncbi.nlm.nih.gov/pubmed/24465754 http://dx.doi.org/10.1371/journal.pone.0085863 |