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Structural Basis of Thermal Stability of the Tungsten Cofactor Synthesis Protein MoaB from Pyrococcus furiosus

Molybdenum and tungsten cofactors share a similar pterin-based scaffold, which hosts an ene-dithiolate function being essential for the coordination of either molybdenum or tungsten. The biosynthesis of both cofactors involves a multistep pathway, which ends with the activation of the metal binding...

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Detalles Bibliográficos
Autores principales: Havarushka, Nastassia, Fischer-Schrader, Katrin, Lamkemeyer, Tobias, Schwarz, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896444/
https://www.ncbi.nlm.nih.gov/pubmed/24465852
http://dx.doi.org/10.1371/journal.pone.0086030