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Sodium fluoride induces apoptosis through the downregulation of hypoxia-inducible factor-1α in primary cultured rat chondrocytes

It has been reported that sodium fluoride (NaF) suppresses the proliferation and induces apoptosis of chondrocytes. However, the cellular and molecular mechanisms of the effect have not been elucidated. Therefore, the aim of this study was to evaluate the mechanisms of the effects of NaF on primary...

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Detalles Bibliográficos
Autores principales: MENG, HONGMEI, ZHANG, TAO, LIU, WEIDONG, WANG, HUAN, WANG, CHUNLEI, ZHAO, ZHE, LIU, NING, WANG, WENBO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896455/
https://www.ncbi.nlm.nih.gov/pubmed/24317498
http://dx.doi.org/10.3892/ijmm.2013.1576