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Structure-Function Analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin Signaling
The evolutionarily conserved Wnt/ß-catenin (Wnt/ß-cat) pathway plays an important role in animal development in metazoans. Many Wnt targets are regulated by members of the TCF/LEF1 (TCF) family of transcription factors. All TCFs contain a High Mobility Group (HMG) domain that bind specific DNA seque...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896468/ https://www.ncbi.nlm.nih.gov/pubmed/24465946 http://dx.doi.org/10.1371/journal.pone.0086180 |