Bcl2 Deficiency Activates FoxO through Akt Inactivation and Accelerates Osteoblast Differentiation

Osteoblast apoptosis plays an important role in bone development and maintenance, and is in part responsible for osteoporosis in sex steroid deficiency, glucocorticoid excess, and aging. Although Bcl2 subfamily proteins, including Bcl2 and Bcl-XL, inhibit apoptosis, the physiological significance of...

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Detalles Bibliográficos
Autores principales: Moriishi, Takeshi, Kawai, Yosuke, Komori, Hisato, Rokutanda, Satoshi, Eguchi, Yutaka, Tsujimoto, Yoshihide, Asahina, Izumi, Komori, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896485/
https://www.ncbi.nlm.nih.gov/pubmed/24466179
http://dx.doi.org/10.1371/journal.pone.0086629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896485/
https://www.ncbi.nlm.nih.gov/pubmed/24466179
http://dx.doi.org/10.1371/journal.pone.0086629

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