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Endocytosis of Fgf8 Is a Double-Stage Process and Regulates Spreading and Signaling

Tightly controlled concentration gradients of morphogens provide positional information and thus regulate tissue differentiation and morphogenesis in multicellular organisms. However, how such morphogenetic fields are formed and maintained remains debated. Here we show that fibroblast growth factor...

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Detalles Bibliográficos
Autores principales: Rengarajan, Charanya, Matzke, Alexandra, Reiner, Luisa, Orian-Rousseau, Véronique, Scholpp, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896487/
https://www.ncbi.nlm.nih.gov/pubmed/24466061
http://dx.doi.org/10.1371/journal.pone.0086373