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Complex Regulation of PKCβ2 and PDK-1/AKT by ROCK2 in Diabetic Heart
OBJECTIVES: The RhoA/ROCK pathway contributes to diabetic cardiomyopathy in part by promoting the sustained activation of PKCβ2 but the details of their interaction are unclear. The purpose of this study was to investigate if over-activation of ROCK in the diabetic heart leads to direct phosphorylat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896488/ https://www.ncbi.nlm.nih.gov/pubmed/24466133 http://dx.doi.org/10.1371/journal.pone.0086520 |