Allosteric Regulation of the Hsp90 Dynamics and Stability by Client Recruiter Cochaperones: Protein Structure Network Modeling

The fundamental role of the Hsp90 chaperone in supporting functional activity of diverse protein clients is anchored by specific cochaperones. A family of immune sensing client proteins is delivered to the Hsp90 system with the aid of cochaperones Sgt1 and Rar1 that act cooperatively with Hsp90 to f...

Descripción completa

Detalles Bibliográficos
Autores principales: Blacklock, Kristin, Verkhivker, Gennady M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896489/
https://www.ncbi.nlm.nih.gov/pubmed/24466147
http://dx.doi.org/10.1371/journal.pone.0086547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896489/
https://www.ncbi.nlm.nih.gov/pubmed/24466147
http://dx.doi.org/10.1371/journal.pone.0086547

Ejemplares similares