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Valproic acid inhibits tumor angiogenesis in mice transplanted with Kasumi-1 leukemia cells

Histone deacetylase (HDAC) inhibitors have been reported to inhibit tumor angiogenesis via the downregulation of angiogenic factors. Our previous in vitro studies demonstrated that valproic acid (VPA) exerted antitumor effects on Kasumi-1 cells, which are human acute myeloid leukemia cells with an 8...

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Detalles Bibliográficos
Autores principales: ZHANG, ZHI-HUA, HAO, CHANG-LAI, LIU, PENG, TIAN, XIA, WANG, LI-HONG, ZHAO, LEI, ZHU, CUI-MIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896514/
https://www.ncbi.nlm.nih.gov/pubmed/24297248
http://dx.doi.org/10.3892/mmr.2013.1834