Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2 m(1) antibody

Antibodies of human IgA isotype are critical components of the mucosal immune system, but little is known about their immunotherapeutic potential. Compared with IgG antibodies, IgA molecules carry a C-terminal tail piece extension of 18 amino acids with a free cysteine at position 471. This cysteine...

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Detalles Bibliográficos
Autores principales: Brunke, Christina, Lohse, Stefan, Derer, Stefanie, Peipp, Matthias, Boross, Peter, Kellner, Christian, Beyer, Thomas, Dechant, Michael, Royle, Louise, Liew, Li Phing, Leusen, Jeanette HW, Valerius, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896607/
https://www.ncbi.nlm.nih.gov/pubmed/24492345
http://dx.doi.org/10.4161/mabs.26396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896607/
https://www.ncbi.nlm.nih.gov/pubmed/24492345
http://dx.doi.org/10.4161/mabs.26396

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