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Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas

BACKGROUND: To gain biological insights into lung metastases from hepatocellular carcinoma (HCC), we compared the whole-genome sequencing profiles of primary HCC and paired lung metastases. METHODS: We used whole-genome sequencing at 33X-43X coverage to profile somatic mutations in primary HCC (HBV+...

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Detalles Bibliográficos
Autores principales: Ouyang, Limei, Lee, Jeeyun, Park, Cheol-Keun, Mao, Mao, Shi, Yujian, Gong, Zhuolin, Zheng, Hancheng, Li, Yingrui, Zhao, Yonggang, Wang, Guangbiao, Fu, Huiling, Kim, Jhingook, Lim, Ho Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896667/
https://www.ncbi.nlm.nih.gov/pubmed/24405831
http://dx.doi.org/10.1186/1755-8794-7-2