Evaluation of in vitro toxicity of peptide (N-acetyl-Leu-Gly-Leu-COOH)-substituted-β-cyclodextrin derivative, a novel drug carrier, in PC-12 cells

BACKGROUND: Cyclodextrins (CDs) have been shown to improve physicochemical and biopharmaceutical properties of drugs when low solubility and low safety limit their use in the pharmaceutical field. Recently, a new amphiphilic peptide-substituted-β-CD, hepta-(N-acetyl-Leu-Gly-Leu)-β-CD (hepta-(N-acety...

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Detalles Bibliográficos
Autores principales: Sadeghnia, Hamid Reza, Vahdati Hassani, Faezeh, Sadeghian, Hamid, Miandehi, Maryam, Hadizadeh, Farzin, Karimi, Gholamreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896683/
https://www.ncbi.nlm.nih.gov/pubmed/24359794
http://dx.doi.org/10.1186/2008-2231-21-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896683/
https://www.ncbi.nlm.nih.gov/pubmed/24359794
http://dx.doi.org/10.1186/2008-2231-21-75

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