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Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200

BACKGROUND: The role of exosomes in the pathogenesis and metastatic spread of cancer remains to be fully elucidated. Recent studies support the hypothesis that the release of exosomes from cells modifies local extracellular conditions to promote cell growth and neovascularisation. In addition, exoso...

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Detalles Bibliográficos
Autores principales: Kobayashi, Miharu, Salomon, Carlos, Tapia, Jorge, Illanes, Sebastian E, Mitchell, Murray D, Rice, Gregory E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896684/
https://www.ncbi.nlm.nih.gov/pubmed/24393345
http://dx.doi.org/10.1186/1479-5876-12-4