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Synthesis and anti-proliferative activity evaluation of N3-acyl-N5-aryl-3,5-diaminoindazole analogues as anti-head and neck cancer agent

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the 11th leading cancer by incidence worldwide. Surgery and radiotherapy have been the major treatment for patients with HNSCC while chemotherapy has become an important treatment option for locally advanced HNSCC. Understanding of the mol...

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Detalles Bibliográficos
Autores principales: Lee, Jinho, Kim, Jina, Hong, Victor Sukbong, Park, Jong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896709/
https://www.ncbi.nlm.nih.gov/pubmed/24393135
http://dx.doi.org/10.1186/2008-2231-22-4