Pharmacokinetics of mirtazapine and its main metabolites after single intravenous and oral administrations in rats at two dose rates

BACKGROUND: Mirtazapine (MRZ) is a human antidepressant drug metabolized to 8-OH mirtazapine (8-OH) and dimethylmirtazapine (DMR) metabolites. Recently, this drug has been proposed as a potential analgesic for use in a multidrug analgesic regime in the context of veterinary medicine. The aim of this...

Descripción completa

Detalles Bibliográficos
Autores principales: Rouini, Mohammad-Reza, Lavasani, Hoda, Sheikholeslami, Behjat, Owen, Helen, Giorgi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896718/
https://www.ncbi.nlm.nih.gov/pubmed/24397986
http://dx.doi.org/10.1186/2008-2231-22-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896718/
https://www.ncbi.nlm.nih.gov/pubmed/24397986
http://dx.doi.org/10.1186/2008-2231-22-13

Ejemplares similares