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A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury

BACKGROUND: Many diseases and pathological conditions are characterized by transient or constitutive overproduction of reactive oxygen species (ROS). ROS are causal for ischemia/reperfusion (IR)-associated tissue injury (IRI), a major contributor to organ dysfunction or failure. Preventing IRI with...

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Detalles Bibliográficos
Autores principales: Ashraf, Muhammad Imtiaz, Ebner, Matthias, Wallner, Christoph, Haller, Martina, Khalid, Sana, Schwelberger, Hubert, Koziel, Katarzyna, Enthammer, Marion, Hermann, Martin, Sickinger, Stephan, Soleiman, Afschin, Steger, Christina, Vallant, Stephanie, Sucher, Robert, Brandacher, Gerald, Santer, Peter, Dragun, Duska, Troppmair, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896752/
https://www.ncbi.nlm.nih.gov/pubmed/24423080
http://dx.doi.org/10.1186/1478-811X-12-6