Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

BACKGROUND: Cross-breeding of transgenic mice is commonly used to assess gene-gene interactions, particularly in the context of disease. Strain background changes can influence the phenotype of mouse models and can confound crossbreeding studies. We sought to determine if changing the strain backgro...

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Detalles Bibliográficos
Autores principales: Bailey, Rachel M, Howard, John, Knight, Joshua, Sahara, Naruhiko, Dickson, Dennis W, Lewis, Jada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896770/
https://www.ncbi.nlm.nih.gov/pubmed/24428919
http://dx.doi.org/10.1186/1750-1326-9-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896770/
https://www.ncbi.nlm.nih.gov/pubmed/24428919
http://dx.doi.org/10.1186/1750-1326-9-8

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