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A patient-specific therapeutic approach for tumour cell population extinction and drug toxicity reduction using control systems-based dose-profile design

BACKGROUND: When anti-tumour therapy is administered to a tumour-host environment, an asymptotic tapering extremity of the tumour cell distribution is noticed. This extremity harbors a small number of residual tumour cells that later lead to secondary malignances. Thus, a method is needed that would...

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Detalles Bibliográficos
Autores principales: Kapoor, Suhela, Rallabandi, VP Subramanyam, Sakode, Chandrashekhar, Padhi, Radhakant, Roy, Prasun K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896771/
https://www.ncbi.nlm.nih.gov/pubmed/24369857
http://dx.doi.org/10.1186/1742-4682-10-68