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CpG sites associated with NRP1, NRXN2 and miR-29b-2 are hypomethylated in monocytes during ageing

BACKGROUND: Ageing affects many components of the immune system, including innate immune cells like monocytes. They are important in the early response to pathogens and for their role to differentiate into macrophages and dendritic cells. Recent studies have revealed significant age-related changes...

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Detalles Bibliográficos
Autores principales: Tserel, Liina, Limbach, Maia, Saare, Mario, Kisand, Kai, Metspalu, Andres, Milani, Lili, Peterson, Pärt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896835/
https://www.ncbi.nlm.nih.gov/pubmed/24405718
http://dx.doi.org/10.1186/1742-4933-11-1