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Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice
BACKGROUND: Maternal diabetes mellitus not only has severe deleterious effects on fetal development, but also it affects transmission to the next generation. However, the underlying mechanisms for these effects are still not clear. METHODS: We investigated the methylation patterns and expressions of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896855/ https://www.ncbi.nlm.nih.gov/pubmed/24378208 http://dx.doi.org/10.1186/1477-7827-11-119 |