Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice

BACKGROUND: Maternal diabetes mellitus not only has severe deleterious effects on fetal development, but also it affects transmission to the next generation. However, the underlying mechanisms for these effects are still not clear. METHODS: We investigated the methylation patterns and expressions of...

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Detalles Bibliográficos
Autores principales: Ge, Zhao-Jia, Liang, Qiu-Xia, Luo, Shi-Ming, Wei, Yan-Chang, Han, Zhi-Ming, Schatten, Heide, Sun, Qing-Yuan, Zhang, Cui-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896855/
https://www.ncbi.nlm.nih.gov/pubmed/24378208
http://dx.doi.org/10.1186/1477-7827-11-119

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