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Evolutionary engineering of a glycerol-3-phosphate dehydrogenase-negative, acetate-reducing Saccharomyces cerevisiae strain enables anaerobic growth at high glucose concentrations

Glycerol production by Saccharomyces cerevisiae, which is required for redox-cofactor balancing in anaerobic cultures, causes yield reduction in industrial bioethanol production. Recently, glycerol formation in anaerobic S. cerevisiae cultures was eliminated by expressing Escherichia coli (acetylati...

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Detalles Bibliográficos
Autores principales: Guadalupe-Medina, Víctor, Metz, Benjamin, Oud, Bart, van Der Graaf, Charlotte M, Mans, Robert, Pronk, Jack T, van Maris, Antonius J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896938/
https://www.ncbi.nlm.nih.gov/pubmed/24004455
http://dx.doi.org/10.1111/1751-7915.12080