Sulindac activates NF-κB signaling in colon cancer cells

BACKGROUND: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is mediated through multiple cellular pathways but is also accompanied by gastrointestinal side effects, such as colon inflammation. We have r...

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Detalles Bibliográficos
Autores principales: Mladenova, Dessislava, Pangon, Laurent, Currey, Nicola, Ng, Irvin, Musgrove, Elizabeth A, Grey, Shane T, Kohonen-Corish, Maija RJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896984/
https://www.ncbi.nlm.nih.gov/pubmed/24083678
http://dx.doi.org/10.1186/1478-811X-11-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896984/
https://www.ncbi.nlm.nih.gov/pubmed/24083678
http://dx.doi.org/10.1186/1478-811X-11-73

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