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Sulindac activates NF-κB signaling in colon cancer cells

BACKGROUND: The non-steroidal anti-inflammatory drug (NSAID) sulindac has shown efficacy in preventing colorectal cancer. This potent anti-tumorigenic effect is mediated through multiple cellular pathways but is also accompanied by gastrointestinal side effects, such as colon inflammation. We have r...

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Detalles Bibliográficos
Autores principales:	Mladenova, Dessislava, Pangon, Laurent, Currey, Nicola, Ng, Irvin, Musgrove, Elizabeth A, Grey, Shane T, Kohonen-Corish, Maija RJ
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896984/ https://www.ncbi.nlm.nih.gov/pubmed/24083678 http://dx.doi.org/10.1186/1478-811X-11-73

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