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Potential of known and short prokaryotic protein motifs as a basis for novel peptide-based antibacterial therapeutics: a computational survey

Short linear motifs (SLiMs) are functional stretches of protein sequence that are of crucial importance for numerous biological processes by mediating protein–protein interactions. These motifs often comprise peptides of less than 10 amino acids that modulate protein–protein interactions. While well...

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Detalles Bibliográficos
Autores principales: Ruhanen, Heini, Hurley, Daniel, Ghosh, Ambarnil, O'Brien, Kevin T., Johnston, Catrióna R., Shields, Denis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896991/
https://www.ncbi.nlm.nih.gov/pubmed/24478765
http://dx.doi.org/10.3389/fmicb.2014.00004