Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

Axonemal dynein complexes are preassembled in the cytoplasm before their transport to cilia, but the mechanism of this process remains unclear. We now show that mice lacking Pih1d3, a PIH1 domain–containing protein, develop normally but manifest male sterility. Pih1d3(−/−) sperm were immotile and fr...

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Detalles Bibliográficos
Autores principales: Dong, Fenglan, Shinohara, Kyosuke, Botilde, Yanick, Nabeshima, Ryo, Asai, Yasuko, Fukumoto, Akemi, Hasegawa, Toshiaki, Matsuo, Moe, Takeda, Hiroyuki, Shiratori, Hidetaka, Nakamura, Tetsuya, Hamada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897177/
https://www.ncbi.nlm.nih.gov/pubmed/24421334
http://dx.doi.org/10.1083/jcb.201304076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897177/
https://www.ncbi.nlm.nih.gov/pubmed/24421334
http://dx.doi.org/10.1083/jcb.201304076

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