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Genome maintenance in pluripotent stem cells

Pluripotent stem cells (PSCs) must maintain their proper genomic content in order to preserve appropriate self-renewal and differentiation capacities. However, their prolonged in vitro propagation, as well as the environmental culture conditions, present serious challenges to genome maintenance. Rec...

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Detalles Bibliográficos
Autores principales: Weissbein, Uri, Benvenisty, Nissim, Ben-David, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897183/
https://www.ncbi.nlm.nih.gov/pubmed/24446481
http://dx.doi.org/10.1083/jcb.201310135